Santa Cruz travel guide
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Santa Cruz

Bolivia’s largest and fastest-growing city, a warm lowland base for Jesuit missions and national parks

Photo by Franco Jonatan Pardo Ichazo (CC BY-SA 4.0) via Wikimedia Commons
LanguageSpanish
CurrencyBOB
CountryBolivia
Best TimeMay – Oct
Plug TypeType A / C (mixed, 220V)
Emergency110 police; 118 ambulance
TimezoneBOT (UTC-4) year-round

Santa Cruz de la Sierra, in Bolivia’s eastern lowlands, is the country’s largest city and its economic centre. Its warm, humid climate and relaxed atmosphere are very different from the highland cities.

The city itself has a pleasant central plaza and cathedral, but most visitors use it as a base for the Jesuit mission towns of Chiquitos, the hilltop ruins at Samaipata and Amboró National Park.

Top Sights in Santa Cruz

The cathedral of Santa Cruz de la Sierra

Cathedral and Plaza 24 de Septiembre

The shady main square is the heart of the city. Climb the cathedral bell tower for a view over the plaza.

Photo: AriomPardo, CC BY-SA 4.0

El Fuerte de Samaipata

Samaipata and El Fuerte

About three hours west, the village of Samaipata is near El Fuerte, a huge carved rock used as a ceremonial site by pre-Inca and Inca peoples. It is a UNESCO World Heritage Site.

Photo: P. Hughes, CC BY 4.0

The mission church at San José de Chiquitos

Jesuit Missions of Chiquitos

East of the city, six mission towns founded by Jesuits in the 17th and 18th centuries still have their churches, a UNESCO World Heritage Site.

Every two years, a baroque music festival is held in the mission towns.

Photo: Geoffrey Groesbeck, CC BY-SA 3.0

Amboró National Park

Amboró National Park

A large protected area where the Andes meet the lowlands, with cloud forest, rivers and hundreds of bird species. Guided trips leave from Samaipata or Buena Vista.

Photo: Stoni111121, CC BY-SA 4.0

Eating & Drinking

Try majadito (rice with dried beef), cuñapé (cheese bread) and sonso (cassava and cheese), plus grilled meat and tropical fruit juices.

The Equipetrol district has many restaurants and bars.

Getting There & Around

Viru Viru International Airport (VVI) has flights from other Bolivian cities and international connections. The bus terminal links Santa Cruz with the rest of the country.

Taxis are cheap; agree fares in advance or use a ride-hailing app. Citizens of the EU, the UK and many other countries do not need a visa for a tourist stay. In December 2025 Bolivia also announced the removal of the visa requirement for US citizens and several other nationalities. Check current rules before you travel.

Best Time to Visit Santa Cruz

Jan
27°C
Hot, rainy
Feb
27°C
Hot, rainy
Mar
27°C
Rainy
Apr
25°C
Drier
May
23°C
Dry, mild
Jun
21°C
Dry, cool fronts
Jul
21°C
Dry, cool fronts
Aug
23°C
Dry
Sep
25°C
Warm, dry
Oct
27°C
Hot
Nov
27°C
Hot, rains begin
Dec
27°C
Hot, rainy

What Does Santa Cruz Cost?

Bolivia uses the boliviano (Bs). It is one of the cheapest countries in South America, but in recent years there have been fuel shortages and a shortage of US dollars, so bring cash and check the current exchange situation.

Budget
US$25–40 / day
Accommodation
Hostel
US$10–20
Food
Local restaurants
US$6–12
Transport
Micros (minibuses)
under US$1

Mid-range
US$60–110 / day
Accommodation
Mid-range hotel
US$45–80
Food
Restaurants
US$15–25
Activities
Samaipata day trip
US$40–70

Splurge
US$180+ / day
Accommodation
Upscale hotel
US$120+
Activities
Multi-day mission circuit tour
US$300+

Prices are approximate.

4 Days from Santa Cruz

City, ruins and forest.

Day 1
City

Explore the plaza, the cathedral and the markets, then dinner in Equipetrol.

Day 2
Samaipata

Travel to Samaipata and visit El Fuerte.

Day 3
Amboro

Take a guided hike in the cloud forest of Amboró.

Day 4
Missions

Return to Santa Cruz, or continue east on a multi-day tour of the Chiquitos missions.

Travel Tips

Heat

It is hot and humid most of the year.

Rain

Heavy rain from December to March can close roads.

Mosquitoes

Use repellent in the lowlands.

Cash

Carry cash; card acceptance can be limited outside the city.

Common Questions about Santa Cruz

Quick answers for planning time in Santa Cruz.

Is Santa Cruz at high altitude?

No, it lies at about 400m in the lowlands, so altitude sickness is not a concern.

How far is Samaipata from Santa Cruz?

About three hours by road.

Are the Jesuit Missions of Chiquitos a UNESCO site?

Yes, they were listed in 1990.

What is El Fuerte de Samaipata?

A large carved rock and ceremonial site near Samaipata, used by pre-Inca and Inca peoples and listed by UNESCO.

When is the best time to visit Santa Cruz?

May to October, the drier and slightly cooler season.

Useful Apps

Useful apps for Bolivia.

Google Maps

Offline maps are essential on the Altiplano, where there is often no signal.

Free

Google Translate

Spanish is the main language; Quechua and Aymara are widely spoken in the highlands.

Free

WhatsApp

Tour agencies, hostels and drivers use WhatsApp.

Free

GetYourGuide

Bookable salt flat, city and archaeological tours.

Free

More in Bolivia

Planning a wider trip? Our Bolivia travel guide covers getting there, costs, when to go and more.

✓Content last reviewed: October 2026 by the traveling-to.com editorial team.
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